64EXTRACTION, ISOLATION AND CHEMICAL COMPOSITION OF THE ESSENTIAL OIL OF RUTA GRAVEOLENS L OF MEKELLE, NORTHERN ETHIOPIAThe constituents of the essential oil isolated by hydrodistillation of the aerial parts of Ruta graveolens L obtained from Mekelle, Northern Ethiopia was examined by GC-MS. The yield of the extracted oil was found to be 0.5% (v/w) on dried weight basis. A total of 13 components were identified accounting for 99.98% of the oil. The major components identified were Undecanone-2 (43.66%), Nonan-2-one (16.09%), 2-Acetoxy tetradecanone (14.49%) and Nonyl cyclopropanecarboxylate (9.22%).mashoh@gmail.comReview512015Essential oil,Hydrodistillation,Rutaceae,Ruta graveolens LMasho Hilawie,C.R.Unnithan,Mehari Muuz,Desta Gebremedhin,D.N.Reddy,Abraha Birhan,Gebremedhin GebremariamDepartment of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia.,Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia.,Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia.,Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia.,Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia.,Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia.,Department of Chemistry, College of Natural and Computational Sciences, Mekelle University, Ethiopia.