146SPICES: A NEW REPOSITORY OF THE ANTI-INFLAMMATORY ACTIVITY- REVIEWInflammation is a localised physical condition in which a portion of the body becomes reddish, swollen, heated, and frequently painful in response to an injury or illness. Inflammation is caused by the immune system being activated in response to a variety of stressors. With cellular and humoral components, the immune system is a highly sophisticated and evolutionarily honed defence mechanism. There are several synthetic medications available to efficiently treat inflammation and associated symptoms, but they are not necessarily without adverse effects. Despite a lack of understanding regarding herbals' pharmacological efficacies and safety, sales of both proven and untested medicines are increasing. This article is a compilation of the anti-inflammatory properties of a few commonly used spicesavyoops@gmail.comReview1212022Spices,Anti-inflammatory,HerbsMandem Sai Sree,Katti Reshma,Kalangi Yedukondalu,Karmuru Keerthi,Juvvalagunta Vinay,Avinash Kumar Reddy GDepartment of Pharmacognosy, Rao’s College of Pharmacy, Venkatachalam, Nellore-524320, Andhra Pradesh, India.,Department of Pharmacognosy, Rao’s College of Pharmacy, Venkatachalam, Nellore-524320, Andhra Pradesh, India.,Department of Pharmacognosy, Rao’s College of Pharmacy, Venkatachalam, Nellore-524320, Andhra Pradesh, India.,Department of Pharmacognosy, Rao’s College of Pharmacy, Venkatachalam, Nellore-524320, Andhra Pradesh, India.,Department of Pharmacognosy, Rao’s College of Pharmacy, Venkatachalam, Nellore-524320, Andhra Pradesh, India.,Department of Pharmacognosy, Rao’s College of Pharmacy, Venkatachalam, Nellore-524320, Andhra Pradesh, India.