123EVALUATION OF SURGICAL PROPHYLACTIC ANTIBIOTIC IN ORTHOPAEDIC DEPARTMENT BY CLINICAL PHARMACISTObjective: The main objective of this study is to evaluate the use of surgical prophylactic antibiotics in orthopaedic department according to WHO guidelines. Study design: An observational and prospective study was conducted in 200 patients of orthopaedic department for a period of 6 months. Basic demographic data, laboratory investigations and details of prophylactic antibiotics being prescribed were collected from the patient’s case sheets. A descriptive analysis was carried out on the data collected. Result: Out of 200 cases, 69.5% of the pre-operative antibiotics prescribed were according to the WHO guidelines. Conclusion: A significant proportion of prescriptions followed the WHO guidelines, but still there is a need to emphasize more on the antibiotic prescribing patterns to prevent antibiotic resistance.praveen.pharmd16@gmail.comResearch912019Prophylaxis, Antibiotics, Orthopaedic surgery.M. Praveen kumar,K. Bhanu Prasad,Nausheen afsar,Pinky R.Donda,Sadaf fatima,Poreddy Srija,N.SriramM. Praveen kumar,K. Bhanu Prasad,Nausheen afsar,Pinky R.Donda,Sadaf fatima,Poreddy Srija,N.Sriram